SCIENCE

Publication

  • Targeting SREBP-dependent Lipid Metabolism for the Treatment of Glioblastoma. In Preparation
  • Cytoplasmic LMO2-LDB1 complex activates STAT3 signaling through interaction with gp130-JAK in glioma stem cells. Under Review. 2022
  • Oncogenic JAG1 intracellular domain is a transcriptional cofactor that acts in concert with DDX17/SMAD3/TGIF2. Under Review. 2022
  • Dihydropyrimidinase-related protein 5 controls glioblastoma stem cell characteristics as a biomarker of proneural-subtype glioblastoma stem cells. Oncology Letters. 2020 Aug;20(2):1153-11
  • ARS2/MAGL signaling in glioblastoma stem cells promotes self-renewal and M2-like polarization of tumor-associated macrophages. Nature Communications. 2020 Jun 12;11(1):2978
  • ABCB7 simultaneously regulates apoptotic and non apoptotic cell death by modulating mitochondrial ROS and HIF1a-driven NFkB signaling. Oncogene. 2020 Feb;39(9):1969-1982
  • Ly6G+ inflammatory cells enable the conversion of cancer cells to cancer stem cells in an irradiated glioblastoma model. Cell Death Differ. 2019 Oct;26(10):2139-2156.
  • Conversion of glioma cells to glioma stem-like cells by angiocrine factors. Biochem Biophys Res Commun. 2018 Feb 19;496(4):1013-1018
  • Inhibition of ID1–BMPR2 Intrinsic Signaling Sensitizes Glioma Stem Cells to Differentiation Therapy. Clinical Cancer Research. 2018;24(2):383-94.
  • The ID1-CULLIN3 axis regulates intracellular SHH and WNT signaling in glioblastoma stem cells. Cell reports. 2016;16(6):1629-41.
  • The LIM-only transcription factor LMO2 determines tumorigenic and angiogenic traits in glioma stem cells. Cell Death Differ. 2015;22(9):1517.
  • Epidermal growth factor receptor variant III renders glioma cancer cells less differentiated by JAGGED1. Tumor Biology. 2015;36(4):2921-8.
  • Crosstalk between glioma-initiating cells and endothelial cells drives tumor progression. Cancer research. 2014;74(16):4482-92.
  • Cell surface Nestin is a biomarker for glioma stem cells. Biochem Biophys Res Commun. 2013;433(4):496-501.
  • Blockade of EGFR signaling promotes glioma stem-like cell invasiveness by abolishing ID3-mediated inhibition of p27KIP1 and MMP3 expression Cancer letters. 2013;328(2):235-42.
  • Interferon regulatory factor 7 regulates glioma stem cells via interleukin-6 and Notch signalling. Brain. 2012;135(4):1055-69.
  • EGFR-AKT-Smad signaling promotes formation of glioma stem-like cells and tumor angiogenesis by ID3-driven cytokine induction. Cancer research. 2011;71(22)7125-34.
  • Identification of a peptide that interacts with Nestin protein expressed in brain cancer stem cells. Biomaterials. 2011;32(33):8518-28.
  • ID4 Imparts chemoresistance and cancer stemness to glioma cells by derepressing miR-9*–mediated suppression of SOX2. Cancer research. 2011;71(9):3410-21.
  • Inhibitor of differentiation 4 drives brain tumor-initiating cell genesis through cyclin E and notch signaling. Genes & development. 2008;22(15):2028-33.